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Elevated transforming growth factor β2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic X receptor α knockout embryos

Septation of the single tubular embryonic outflow tract into two outlet segments in the heart requires the precise integration of proliferation, differentiation and apoptosis during remodeling. Lack of proper coordination between these processes would result in a variety of congenital cardiac defect...

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Detalhes bibliográficos
Main Authors: Kubalak, Steven W., Hutson, D. Reneé, Scott, Karen K., Shannon, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094159/
https://ncbi.nlm.nih.gov/pubmed/11830573
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