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Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L

Expression of vascular endothelial growth factor-A (VEGFA) by tumour-associated macrophages is critical for tumour progression and metastasis. Hypoxia, a common feature of the neoplastic microenvironment, induces VEGFA expression by increased transcription, translation, and mRNA stabilization. Here,...

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Detalhes bibliográficos
Main Authors: Jafarifar, Faegheh, Yao, Peng, Eswarappa, Sandeepa M, Fox, Paul L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094116/
https://ncbi.nlm.nih.gov/pubmed/21343907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.38
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