Conformational changes underlying calcium/calmodulin-dependent protein kinase II activation

Calcium/calmodulin-dependent protein kinase II (CaMKII) interprets information conveyed by the amplitude and frequency of calcium transients by a controlled transition from an autoinhibited basal intermediate to an autonomously active phosphorylated intermediate (De Koninck and Schulman, 1998). We u...

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Main Authors: Hoffman, Laurel, Stein, Richard A, Colbran, Roger J, Mchaourab, Hassane S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094114/
https://ncbi.nlm.nih.gov/pubmed/21343908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.40
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