Viral factor TAV recruits TOR/S6K1 signalling to activate reinitiation after long ORF translation

The protein kinase TOR (target-of-rapamycin) upregulates translation initiation in eukaryotes, but initiation restart after long ORF translation is restricted by largely unknown pathways. The plant viral reinitiation factor transactivator–viroplasmin (TAV) exceptionally promotes reinitiation through...

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Hlavní autoři: Schepetilnikov, Mikhail, Kobayashi, Kappei, Geldreich, Angèle, Caranta, Carole, Robaglia, Christophe, Keller, Mario, Ryabova, Lyubov A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094109/
https://ncbi.nlm.nih.gov/pubmed/21343906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.39
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