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The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse
During antigen-specific T-cell activation, mitochondria mobilize towards the vicinity of the immune synapse. We show here that the mitochondrial fission factor dynamin-related protein 1 (Drp1) docks at mitochondria, regulating their positioning and activity near the actin-rich ring of the peripheral...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094108/ https://ncbi.nlm.nih.gov/pubmed/21326213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.25 |
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