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Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death

Cell death provokes a robust inflammatory response. We have previously shown that this response is dependent on IL-α. Here we investigate the cellular mechanism used by a host to sense cell death, produce IL-α and also the role of IL-β in this response. In almost all cases examined, the IL-1 that st...

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Detalhes bibliográficos
Main Authors: Kono, Hajime, Karmarkar, Dipti, Iwakura, Yoichiro, Rock, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094104/
https://ncbi.nlm.nih.gov/pubmed/20220089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902485
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