Cyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3

Mice deficient in Notch3 have defects in arterial vascular smooth muscle cell (VSMC) mechanosensitivity, including impaired myogenic responses and autoregulation, and inappropriate VMSC orientation. Experiments were performed to determine if Notch3 is activated by mechanical stimulation and contribu...

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Detalhes bibliográficos
Main Authors: Zhu, Jian-Hong, Chen, Chun-Lin, Flavahan, Sheila, Harr, Jennifer, Su, Baogen, Flavahan, Nicholas A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Signaling and Stress Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094076/
https://ncbi.nlm.nih.gov/pubmed/21169401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00535.2010
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