RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42

The pathogen Salmonella Typhimurium is a common cause of diarrhea and invades the gut tissue by injecting a cocktail of virulence factors into epithelial cells, triggering actin rearrangements, membrane ruffling and pathogen entry. One of these factors is SopE, a G-nucleotide exchange factor for the...

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Hlavní autoři: Misselwitz, Benjamin, Dilling, Sabrina, Vonaesch, Pascale, Sacher, Raphael, Snijder, Berend, Schlumberger, Markus, Rout, Samuel, Stark, Manuel, Mering, Christian von, Pelkmans, Lucas, Hardt, Wolf-Dietrich
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094068/
https://ncbi.nlm.nih.gov/pubmed/21407211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.7
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