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Vitronectin accumulates in the interstitium but minimally impacts fibrogenesis in experimental chronic kidney disease

Vitronectin (Vtn) is a glycoprotein found in normal serum and pathological extracellular matrix. Given its known interactions with plasminogen activator inhibitor-1 (PAI-1) and Vtn cellular receptors, especially αvβ3 integrin and the urokinase receptor (uPAR), this study was designed to investigate...

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Detalhes bibliográficos
Main Authors: López-Guisa, Jesús M., Rassa, Allen C., Cai, Xiaohe, Collins, Sarah J., Eddy, Allison A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094052/
https://ncbi.nlm.nih.gov/pubmed/21270094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00701.2010
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