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Vitronectin accumulates in the interstitium but minimally impacts fibrogenesis in experimental chronic kidney disease
Vitronectin (Vtn) is a glycoprotein found in normal serum and pathological extracellular matrix. Given its known interactions with plasminogen activator inhibitor-1 (PAI-1) and Vtn cellular receptors, especially αvβ3 integrin and the urokinase receptor (uPAR), this study was designed to investigate...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094052/ https://ncbi.nlm.nih.gov/pubmed/21270094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00701.2010 |
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