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Peptide Labeling with Isobaric Tags Yields Higher Identification Rates Using iTRAQ 4-Plex Compared to TMT 6-Plex and iTRAQ 8-Plex on LTQ Orbitrap
Peptide labeling with isobaric tags has become a popular technique in quantitative shotgun proteomics. Using two different samples viz. a protein mixture and HeLa extracts, we show that three commercially available isobaric tags differ with regard to peptide identification rates: The number of ident...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2010
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093924/ https://ncbi.nlm.nih.gov/pubmed/20593797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac100890k |
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