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Endospanins Regulate a Postinternalization Step of the Leptin Receptor Endocytic Pathway
Endospanin-1 is a negative regulator of the cell surface expression of leptin receptor (OB-R), and endospanin-2 is a homologue of unknown function. We investigated the mechanism for endospanin-1 action in regulating OB-R cell surface expression. Here we show that endospanin-1 and -2 are small integr...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093871/ https://ncbi.nlm.nih.gov/pubmed/21454707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224857 |
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