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Mechanical Stretch Induces Epithelial-Mesenchymal Transition in Alveolar Epithelia via Hyaluronan Activation of Innate Immunity

Epithelial injury is a central event in the pathogenesis of many inflammatory and fibrotic lung diseases like acute respiratory distress syndrome, pulmonary fibrosis, and iatrogenic lung injury. Mechanical stress is an often underappreciated contributor to lung epithelial injury. Following injury, d...

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Detalhes bibliográficos
Main Authors: Heise, Rebecca L., Stober, Vandy, Cheluvaraju, Chaitra, Hollingsworth, John W., Garantziotis, Stavros
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093817/
https://ncbi.nlm.nih.gov/pubmed/21398522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137273
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