A novel method for site specific introduction of single model oxidative DNA lesions into oligodeoxyribonucleotides.
Calf thymus terminal deoxynucleotidyl transferase was used to incorporate several products of oxidative base damage onto the 3' end of oligodeoxyribonucleotides. Under the defined conditions described in this report, single residues of dihydrothymine, beta-ureidoisobutyric acid, thymine glycol, urea...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8479906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.7.1563 |
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