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Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths

Vaccines against human helminths are being developed but the choice of optimal parasitological endpoints and effect measures to assess their efficacy has received little attention. Assuming negative binomial distributions for the parasite counts, we rank the statistical power of three measures of ef...

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Hlavní autoři: Alexander, Neal, Cundill, Bonnie, Sabatelli, Lorenzo, Bethony, Jeffrey M., Diemert, David, Hotez, Peter, Smith, Peter G., Rodrigues, Laura C., Brooker, Simon
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093614/
https://ncbi.nlm.nih.gov/pubmed/21435404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.03.026
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