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Structural Formation of Huntingtin Exon 1 Aggregates Probed by Small-Angle Neutron Scattering

In several neurodegenerative disorders, including Huntington's disease, aspects concerning the earliest of protein structures that form along the aggregation pathway have increasingly gained attention because these particular species are likely to be neurotoxic. We used time-resolved small-angl...

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Autors principals: Stanley, Christopher B., Perevozchikova, Tatiana, Berthelier, Valerie
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093554/
https://ncbi.nlm.nih.gov/pubmed/21575585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.022
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