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Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)–dependent TGF-β signaling

Stem cell antigen (Sca)-1/Ly6A, a glycerophosphatidylinositol-linked surface protein, was found to be associated with murine stem cell– and progenitor cell–enriched populations, and also has been linked to the capacity of tumor-initiating cells. Despite these interesting associations, this protein&#...

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Detalhes bibliográficos
Main Authors: Upadhyay, Geeta, Yin, Yuzhi, Yuan, Hongyan, Li, Xin, Derynck, Rik, Glazer, Robert I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093514/
https://ncbi.nlm.nih.gov/pubmed/21518866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103441108
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