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Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)–dependent TGF-β signaling
Stem cell antigen (Sca)-1/Ly6A, a glycerophosphatidylinositol-linked surface protein, was found to be associated with murine stem cell– and progenitor cell–enriched populations, and also has been linked to the capacity of tumor-initiating cells. Despite these interesting associations, this protein...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093514/ https://ncbi.nlm.nih.gov/pubmed/21518866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103441108 |
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