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Dynamic programming procedure for searching optimal models to estimate substitution rates based on the maximum-likelihood method
The substitution rate in a gene can provide valuable information for understanding its functionality and evolution. A widely used method to estimate substitution rates is the maximum-likelihood method implemented in the CODEML program in the PAML package. A limited number of branch models, chosen ba...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093512/ https://ncbi.nlm.nih.gov/pubmed/21521791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018621108 |
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