Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development

Translational control of many mRNAs in developing metazoan embryos is achieved by alterations in their poly(A) tail length. A family of cytoplasmic poly(A)-binding proteins (PABPs) bind the poly(A) tail and can regulate mRNA translation and stability. However, despite the extensive biochemical chara...

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Detalhes bibliográficos
Main Authors: Gorgoni, Barbara, Richardson, William A., Burgess, Hannah M., Anderson, Ross C., Wilkie, Gavin S., Gautier, Philippe, Martins, Joao P. Sousa, Brook, Matthew, Sheets, Michael D., Gray, Nicola K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093506/
https://ncbi.nlm.nih.gov/pubmed/21518916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017664108
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