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Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

Hypoxia-inducible factor (HIF) is the key transcriptional effector of the hypoxia response in eukaryotes, coordinating the expression of genes involved in oxygen transport, glycolysis, and angiogenesis to promote adaptation to low oxygen levels. HIF is a basic helix-loop-helix (bHLH)-PAS (PER-ARNT-S...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Partch, Carrie L., Gardner, Kevin H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093465/
https://ncbi.nlm.nih.gov/pubmed/21512126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101357108
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