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Transgenic expression of human S100A12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation

BACKGROUND: The calcium binding protein S100A12 is highly upregulated in the serum and sputum of patients with allergic asthma and is suggested to be a biomarker and pathologic mediator of asthma. OBJECTIVE: To test the role of S100A12 in mediating airway inflammation in a mouse model of allergic lu...

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Detalhes bibliográficos
Main Authors: Hofmann Bowman, Marion A., Heydemann, Ahlke, Gawdzik, Joe, Shilling, Rebecca A., Camoretti-Mercado, Blanca
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093439/
https://ncbi.nlm.nih.gov/pubmed/21418345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2011.03714.x
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