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Template controlled coupling and recombination of oligonucleotide blocks containing thiophosphoryl groups.
Oxidation of a pair of 3'- and 5'-thiophosphoryloligonucleotides in the presence of a complementary oligonucleotide template is shown to provide an effective means for selectively linking oligonucleotide blocks. Coupling proceeds rapidly and efficiently under mild conditions in dilute aque...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1993
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309325/ https://ncbi.nlm.nih.gov/pubmed/8464731 |
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