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Normal Neutrophil Maturation is Associated with Selective Loss of MAP Kinase Activation by G-CSF
Although both GM-CSF and G-CSF activate p42/44 MAPK in neutrophil progenitors, the ability of G-CSF to cause MAPK activation is lost in mature neutrophils, while GM-CSF exposure still causes activation. The mechanism of this differential effect related to maturation status has not been explored. We...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093195/ https://ncbi.nlm.nih.gov/pubmed/15541478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2004.05.009 |
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