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Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complex

Despite the lack of an exon junction complex (EJC), Saccharomyces cerevisiae contains Fal1p, a DEAD-box helicase highly homologous to eIF4AIII. We show that yeast Fal1p is functionally orthologous to human eIF4AIII, since expression of human eIF4AIII complements both the lethal phenotype and the 18S...

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Bibliografiset tiedot
Päätekijät: Alexandrov, Andrei, Colognori, David, Steitz, Joan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093123/
https://ncbi.nlm.nih.gov/pubmed/21576267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2045411
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