Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

Genome-wide association studies (GWAS) have identified more than 30 prostate cancer (PrCa) susceptibility loci. One of these (rs2735839) is located close to a plausible candidate susceptibility gene, KLK3, which encodes prostate-specific antigen (PSA). PSA is widely used as a biomarker for PrCa dete...

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Bibliografski detalji
Glavni autori: Kote-Jarai, Z., Amin Al Olama, A., Leongamornlert, D., Tymrakiewicz, M., Saunders, E., Guy, M., Giles, G. G., Severi, G., Southey, M., Hopper, J. L., Sit, K. C., Harris, J. M., Batra, J., Spurdle, A. B., Clements, J. A., Hamdy, F., Neal, D., Donovan, J., Muir, K., Pharoah, P. D. P., Chanock, S. J., Brown, N., Benlloch, S., Castro, E., Mahmud, N., O’Brien, L., Hall, A., Sawyer, E., Wilkinson, R., Easton, D. F., Eeles, R. A.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2011
Teme:
Original Investigation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092928/
https://ncbi.nlm.nih.gov/pubmed/21465221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-0981-1
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