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Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis

For the improved production of vaccines and therapeutic proteins, a detailed understanding of the metabolic dynamics during batch or fed-batch production is requested. To study the new human cell line AGE1.HN, a flexible metabolic flux analysis method was developed that is considering dynamic change...

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Detalhes bibliográficos
Main Authors: Niklas, Jens, Schräder, Eva, Sandig, Volker, Noll, Thomas, Heinzle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092918/
https://ncbi.nlm.nih.gov/pubmed/21188421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-010-0502-y
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