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Conformational Dynamics of Recoverin’s Ca(2+)-myristoyl Switch Probed by (15)N NMR Relaxation Dispersion and Chemical Shift Analysis

Recoverin, a member of the neuronal calcium sensor (NCS) branch of the calmodulin superfamily, serves as a calcium sensor in retinal rod cells. Ca(2+)-induced conformational changes in recoverin promote extrusion of its covalently attached myristate, known as the Ca(2+)-myristoyl switch. Here we pre...

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Detalhes bibliográficos
Main Authors: Xu, Xianzhong, Ishima, Rieko, Ames, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092842/
https://ncbi.nlm.nih.gov/pubmed/21465563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23014
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