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CRF receptor blockade prevents initiation and consolidation of stress effects on affect in the predator stress model of PTSD

Post traumatic stress disorder (PTSD) is a chronic anxiety disorder initiated by an intensely threatening, traumatic event. There is a great need for more efficacious pharmacotherapy and preventive treatments for PTSD. In animals, corticotropin-releasing factor (CRF) and the CRF(1) receptor play a c...

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Autori principali: Adamec, Robert, Fougere, Dennis, Risbrough, Victoria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092595/
https://ncbi.nlm.nih.gov/pubmed/19751543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145709990496
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