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Computational studies of NMDA receptors: differential effects of neuronal activity on efficacy of competitive and non-competitive antagonists
N-Methyl-D-Aspartate receptors (NMDARs) play important physiological as well as pathological roles in the central nervous system (CNS). While NMDAR competitive antagonists, such as D-2-Amino-5-Phosphopentanoic acid (AP5) have been shown to impair learning and memory, the non-competitive antagonist,...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092546/ https://ncbi.nlm.nih.gov/pubmed/21572937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OAB.S7246 |
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