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Driving Catalyst Reoxidation in Wacker Cyclizations with Acetal-Based Metal-Hydride Abstractors

In traditional Wacker processes, Pd(II) becomes reduced to Pd(0) after C-O bond formation and β-H elimination and must be reoxidized to the electrophilic Pd(II) state via a stoichiometric oxidant like benzoquinone, CuCl(2), or O(2). We report herein a Pt-catalyzed Wacker-type process that regenerate...

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Main Authors: Cochrane, Nikki A., Brookhart, Maurice S., Gagné, Michel R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092479/
https://ncbi.nlm.nih.gov/pubmed/21572581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/om2001958
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