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Recovery from μ-Opioid Receptor Desensitization after Chronic Treatment with Morphine and Methadone

Chronic treatment with morphine results in a decrease in μ-opioid receptor sensitivity, an increase in acute desensitization, and a reduction in the recovery from acute desensitization in locus ceruleus neurons. With acute administration, morphine is unlike many other opioid agonists in that it does...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Quillinan, Nidia, Lau, Elaine K., Virk, Michael, von Zastrow, Mark, Williams, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092436/
https://ncbi.nlm.nih.gov/pubmed/21430144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4874-10.2011
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