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Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes
Lymphangiogenesis plays an important role in tumor metastasis and transplant outcome. Here, we show that thrombospondin-1 (TSP-1), a multifunctional extracellular matrix protein and naturally occurring inhibitor of angiogenesis inhibits lymphangiogenesis in mice. Compared with wild-type mice, 6-mo-o...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092349/ https://ncbi.nlm.nih.gov/pubmed/21536744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092277 |
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