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Stereoselectivity in Oxyallyl–Furan 4+3 Cycloadditions: Control of Intermediate Conformations and Dispersive Stabilisation with Evans’ Oxazolidinones

Chiral oxazolidinones were previously thought to control cycloaddition stereoselectivity by steric crowding of one face of the substrate. We have discovered that in 4+3 cycloaddition reactions of oxallyls, the stereoinduction is caused instead by stabilising CH–π interactions that lead to reaction a...

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Detalhes bibliográficos
Main Authors: Krenske, Elizabeth H., Houk, K. N., Lohse, Andrew G., Antoline, Jennifer E., Hsung, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092307/
https://ncbi.nlm.nih.gov/pubmed/21572919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C0SC00280A
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