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Mining electron density for functionally relevant protein polysterism in crystal structures

This review focuses on conceptual and methodological advances in our understanding and characterization of the conformational heterogeneity of proteins. Focusing on X-ray crystallography, we describe how polysterism, the interconversion of pre-existing conformational substates, has traditionally bee...

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Bibliografische gegevens
Hoofdauteurs: Fraser, James S., Jackson, Colin J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SP Birkhäuser Verlag Basel 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092063/
https://ncbi.nlm.nih.gov/pubmed/21190057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0611-4
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