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Mining electron density for functionally relevant protein polysterism in crystal structures

This review focuses on conceptual and methodological advances in our understanding and characterization of the conformational heterogeneity of proteins. Focusing on X-ray crystallography, we describe how polysterism, the interconversion of pre-existing conformational substates, has traditionally bee...

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書誌詳細
主要な著者: Fraser, James S., Jackson, Colin J.
フォーマット: Artigo
言語:Inglês
出版事項: SP Birkhäuser Verlag Basel 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092063/
https://ncbi.nlm.nih.gov/pubmed/21190057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0611-4
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