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Mining electron density for functionally relevant protein polysterism in crystal structures
This review focuses on conceptual and methodological advances in our understanding and characterization of the conformational heterogeneity of proteins. Focusing on X-ray crystallography, we describe how polysterism, the interconversion of pre-existing conformational substates, has traditionally bee...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SP Birkhäuser Verlag Basel
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092063/ https://ncbi.nlm.nih.gov/pubmed/21190057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0611-4 |
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