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Mining electron density for functionally relevant protein polysterism in crystal structures

This review focuses on conceptual and methodological advances in our understanding and characterization of the conformational heterogeneity of proteins. Focusing on X-ray crystallography, we describe how polysterism, the interconversion of pre-existing conformational substates, has traditionally bee...

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Sonraí Bibleagrafaíochta
Main Authors: Fraser, James S., Jackson, Colin J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: SP Birkhäuser Verlag Basel 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092063/
https://ncbi.nlm.nih.gov/pubmed/21190057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0611-4
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