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Mining electron density for functionally relevant protein polysterism in crystal structures
This review focuses on conceptual and methodological advances in our understanding and characterization of the conformational heterogeneity of proteins. Focusing on X-ray crystallography, we describe how polysterism, the interconversion of pre-existing conformational substates, has traditionally bee...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SP Birkhäuser Verlag Basel
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092063/ https://ncbi.nlm.nih.gov/pubmed/21190057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0611-4 |
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