GLYCOGEN SYNTHASE KINASE-3 NEGATIVELY REGULATES TISSUE FACTOR EXPRESSION IN MONOCYTES INTERACTING WITH ACTIVATED PLATELETS

BACKGROUND: At the site of vascular injury monocytes (MN) interacting with activated platelets (PLT) synthesize tissue factor (TF) and promote thrombus formation. Intracellular signals necessary for the expression of TF in MN, in the context of a developing thrombus, remain unknown. OBJECTIVE: The s...

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Main Authors: Di Santo, A., Amore, C., Dell'Elba, G., Manarini, S., Evangelista, V.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091995/
https://ncbi.nlm.nih.gov/pubmed/21320285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04236.x
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