Direct activation of STAT5 by ETV6-LYN fusion protein promotes induction of myeloproliferative neoplasm with myelofibrosis

Myeloproliferative neoplasms (MPN), a group of haematopoietic stem cell (HSC) disorders, are often accompanied by myelofibrosis. We previously identified the fusion of the ETV6 gene to the LYN gene (ETV6-LYN) in idiopathic myelofibrosis with ins(12;8)(p13;q11q21). The introduction of ETV6-LYN into H...

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Main Authors: Takeda, Yusuke, Nakaseko, Chiaki, Tanaka, Hiroaki, Takeuchi, Masahiro, Yui, Makiko, Saraya, Atsunori, Miyagi, Satoru, Wang, Changshan, Tanaka, Satomi, Ohwada, Chikako, Sakaida, Emiko, Yamaguchi, Naoto, Yokote, Koutaro, Hennighausen, Lothar, Iwama, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091948/
https://ncbi.nlm.nih.gov/pubmed/21492125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08663.x
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