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Evolutionary Conservation of the Functional Modularity of Primate and Murine LINE-1 Elements

LINE-1 (L1) retroelements emerged in mammalian genomes over 80 million years ago with a few dominant subfamilies amplifying over discrete time periods that led to distinct human and mouse L1 lineages. We evaluated the functional conservation of L1 sequences by comparing retrotransposition rates of c...

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Detalhes bibliográficos
Main Authors: Wagstaff, Bradley J., Barnerβoi, Miriam, Roy-Engel, Astrid M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091869/
https://ncbi.nlm.nih.gov/pubmed/21572950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019672
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