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Comparing tumor rates in current and historical control groups in rodent cancer bioassays

When evaluating carcinogenicity, tumor rates from the current study are informally assessed within the context of relevant historical control tumor rates. Current rates outside the range of historical rates raise concerns. We propose a statistical procedure that formally compares tumor rates in curr...

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Detalhes bibliográficos
Main Authors: Dinse, Gregg E., Peddada, Shyamal D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091821/
https://ncbi.nlm.nih.gov/pubmed/21566728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1198/sbr.2010.09044
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