Structure/function analysis of the Ala116-->Lys121 region of endonuclease V by random targeted mutagenesis.
Endonuclease V is the product of the denV gene of bacteriophage T4 and is responsible for the recognition and repair of pyrimidine dimers due to UV irradiation of DNA. This is accomplished by a two-step mechanism involving incision at the site of the lesion followed by cleavage of the phosphate back...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
1993
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| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441681/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.3.727 |
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