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Is human blood a good surrogate for brain tissue in transcriptional studies?
BACKGROUND: Since human brain tissue is often unavailable for transcriptional profiling studies, blood expression data is frequently used as a substitute. The underlying hypothesis in such studies is that genes expressed in brain tissue leave a transcriptional footprint in blood. We tested this hypo...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091510/ https://ncbi.nlm.nih.gov/pubmed/20961428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-589 |
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