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Reversed Expression of the JAK/STAT Pathway Related Proteins Prolactin Receptor and STAT5a in Normal and Abnormal Breast Epithelial Cells

The JAK/STAT pathway is important for cellular metabolism. One component, STAT5a, is activated in the breast upon prolactin to prolactin receptor (PRLR) binding facilitating the transcription of genes involved in lobule development. STAT5a was previously found to be expressed in most normal breast e...

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Detalhes bibliográficos
Main Authors: Bratthauer, Gary L., Strauss, Brian L., Barner, Ross
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091403/
https://ncbi.nlm.nih.gov/pubmed/21655368
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