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Chemical and Enzyme-Assisted Syntheses of Norbuprenorphine-3-β-D-Glucuronide
Norbuprenorphine-3-β-D-glucuronide (nBPN-3-β-D-G, 1) is a major phase II metabolite of buprenorphine, a pharmaceutical used for the treatment of opioid addiction. The pharmacological activity of compound 1 is not clear because investigations have been limited by the lack of chemically pure, well cha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091394/ https://ncbi.nlm.nih.gov/pubmed/21434652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100550u |
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