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Toll-like Receptor 3 (TLR3) Induces Apoptosis via Death Receptors and Mitochondria by Up-regulating the Transactivating p63 Isoform α (TAP63α)

Toll-like receptor 3 (TLR3), a member of the pathogen recognition receptors, is widely expressed in various cells and has been shown to activate immune signaling pathways by recognizing viral double-stranded RNA. Recently, it was reported that the activation of TLR3 induced apoptosis in some cells,...

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Hlavní autoři: Sun, Ruili, Zhang, Yu, Lv, Qingshan, Liu, Bei, Jin, Miao, Zhang, Weijia, He, Qing, Deng, Minjie, Liu, Xueting, Li, Guancheng, Li, Yuehui, Zhou, Guohua, Xie, Pingli, Xie, Xiumei, Hu, Jinyue, Duan, Zhaojun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091201/
https://ncbi.nlm.nih.gov/pubmed/21367858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178798
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