Moderate Calcium Channel Dysfunction in Adult Mice with Inducible Cardiomyocyte-specific Excision of the cacnb2 Gene

The major L-type voltage-gated calcium channels in heart consist of an α1C (Ca(V)1.2) subunit usually associated with an auxiliary β subunit (Ca(V)β2). In embryonic cardiomyocytes, both the complete and the cardiac myocyte-specific null mutant of Ca(V)β2 resulted in reduction of L-type calcium curre...

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Detalhes bibliográficos
Main Authors: Meissner, Marcel, Weissgerber, Petra, Londoño, Juan E. Camacho, Prenen, Jean, Link, Sabine, Ruppenthal, Sandra, Molkentin, Jeffery D., Lipp, Peter, Nilius, Bernd, Freichel, Marc, Flockerzi, Veit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091197/
https://ncbi.nlm.nih.gov/pubmed/21357697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227819
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