Functional Coupling of Rab3-interacting Molecule 1 (RIM1) and L-type Ca(2+) Channels in Insulin Release

Insulin release by pancreatic β-cells is regulated by diverse intracellular signals, including changes in Ca(2+) concentration resulting from Ca(2+) entry through voltage-gated (Ca(V)) channels. It has been reported that the Rab3 effector RIM1 acts as a functional link between neuronal Ca(V) channel...

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Bibliographic Details
Main Authors: Gandini, María A., Sandoval, Alejandro, González-Ramírez, Ricardo, Mori, Yasuo, de Waard, Michel, Felix, Ricardo
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091184/
https://ncbi.nlm.nih.gov/pubmed/21402706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187757
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