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Tumor secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumor immune response in vivo

PURPOSE: We employed a grp170-secreting tumor cell system to determine whether tumor cells engineered to secrete grp170 generate an anti-tumor specific immune response. Further, we examine the possibility that secreted grp170 can bind to and co-transport out of tumor cells full-length tumor antigens...

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Detalhes bibliográficos
Main Authors: Arnouk, Hilal, Zynda, Evan R., Wang, Xiang-Yang, Hylander, Bonnie L., Manjili, Masoud H., Repasky, Elizabeth A., Subjeck, John R., Kazim, A. Latif
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091026/
https://ncbi.nlm.nih.gov/pubmed/20210603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02656730903485910
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