Facile preparation of nuclease resistant 3' modified oligodeoxynucleotides.

An efficient chemical procedure for the immobilization of carboxylate containing conjugate groups onto controlled pore glass (CPG) is described. The derivatized supports were used in the automated synthesis of an oligodeoxynucleotide (20-mer ODN) containing a 3' phosphodiester linked hexanol, a...

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Detalhes bibliográficos
Main Authors: Gamper, H B, Reed, M W, Cox, T, Virosco, J S, Adams, A D, Gall, A A, Scholler, J K, Meyer, R B
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC309076/
https://ncbi.nlm.nih.gov/pubmed/8382790
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